Score	Title	Subscore	Description	Associated management recommendation
	0	Not scored		New baseline, incomplete study, or otherwise unable to categorize	Continued follow-up, no change
	1	Imaging improvement	1a – Improvement	Improvement in imaging findings suspected to reflect decreasing tumor burden and/or improving treatment effect	Continued follow-up, no change
			1b – Medication effect	Improvement in imaging findings potentially due to effect from medications such as increasing steroids or initiating avastin	Continued follow-up, no change
	2	No change		No appreciable change from the prior	Continued follow-up, no change
	3	Imaging worsening	3a – Favor treatment effect	Worsening imaging findings favored to represent treatment effects, including radiation therapy and medications	Decreased time interval of follow-up
			3b – Indeterminate	Worsening imaging findings favored to represent an indeterminate mix of treatment effect and tumor worsening	Decreased time interval of follow-up
			3c – Favor tumor progression	Worsening imaging findings favored to represent increasing burden of tumor	Consider change in management vs. Decreased time interval of follow-up
	4	Imaging worsening		Worsening of imaging findings highly suspicious for tumor progression	Consider change in management